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Part 2 of our series on

Von Willebrand's

Disease: Symptoms















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Symptoms of Von Willebrand's Disease that occurs in Dogs
By: Tippy & Turbo



Other dogs more seriously affected by Von Willebrand's Disease
in dogs may have bouts of bleeding from the urinary tract,
reproductive organs, nose, or gums, or hemorrhaging under
the skin. At this point the dog will need a blood transfusion.

There are three classifications of Von Willebrand's Disease.


In Type I, the dog's body has all of the necessary
multimers, but in deficient quantities. This produces
frequent bleeding from the dog's orifices. Doberman
Pinschers,
Shetland Sheepdogs, German Shepherds, Golden
Retrievers,
Poodles, Airedales and Corgis are some of the
breeds that often have this version.

In Type II some of the multimers are missing, and this
version can cause serious bleeding. This version is more
common in German Shorthaired and Wirehaired Pointers.

Type III is the most severe form and the dogs have almost
none of the necessary factor. Dogs with this form can bleed
to death. Breeds most commonly diagnosed with this type are
Chesapeake Bay Retrievers, German Shorthaired and Wirehaired
Pointers and Scottish Terriers.

There are some tests that can discover the disorder in dogs
that haven't shown the clinical symptoms, but unless the
disorder is known to be a problem the dogs are not likely to
be tested before breeding, so the disease continues to be
passed on to offspring by parents that are asymptomatic
carriers.

If you are breeding one of the breeds that are more likely
to carry this genetic disorder, you should have the parents
and the resulting puppies tested.

Since dogs with Von Willebrand's Disease don't always have a
clotting problem, the blood must be tested for Von
Willebrand's Factor Antigen (VWFAg). The result is a
percentage, and normal is between sixty and one hundred and
seventy percent.

Animals that test below seventy percent should be only bred
to mates that test well above seventy percent, and the
resulting puppies should all be tested. If any puppies test
at below fifty percent, neither the puppies nor the low-
testing parents should be bred.




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